Lu-177 supply
Reactors, processors and supply notices for Lutetium-177, with sources and dates.
Supply chain
From irradiation to regional supply. Choose a facility or region to follow its connections.
Reactors
Irradiation
Processors
Separation and processing
Regions served
Regional supply
Each curve represents a relationship documented in public sources, not a contract. Curves have a uniform width, with no volume scale.
Sources of the relationships
- HFRCurium Petten
- NRG PALLAS, Molybdenum-99 (targets irradiated in Petten, separation by Curium)
- NRG PALLAS, NRG and Curium sign multi-year isotope production contract (HFR produces the isotopes Curium uses)
- Curium, Curium extends irradiation partnership with NRG PALLAS for Lu-177 (Lu-177 production lines in Petten)
- NRG PALLAS, Iridium-192 (Ir-192 production in Petten, processed into sources by Curium on the same site)
- Curium, first North American manufacturer offering exclusively 100 % LEU generators (irradiation partners HFR, MARIA and BR2)
- MARIAPOLATOM
- SAFARI-1NTP Radioisotopes
- Necsa, SAFARI-1 (Mo-99 feedstock for NTP Radioisotopes)
- NTP Radioisotopes, SAFARI-1 (about a quarter of global Mo-99 demand, I-131 and Lu-177)
- ITM, ITM and NTP manufacturing and supply agreement for n.c.a. Lu-177 (Yb-176 irradiated in SAFARI-1)
- National Academies, Molybdenum-99 for Medical Imaging (2016), ch. 3 Global Production of Molybdenum-99
- OPALANSTO Health (Lucas Heights)
- ANSTO, Nuclear medicine facilities (OPAL target plates to the Mo-99 Manufacturing Facility; Gentech generators; Australia and the region)
- ANSTO, Introduction to ANSTO 2023 (OPAL irradiation positions for Mo-99, I-131 and Lu-177; exports to the US East Coast)
- National Academies, Molybdenum-99 for Medical Imaging (2016), ch. 3 Global Production of Molybdenum-99
- RA-3CNEA Ezeiza
- IEA-R1IPEN São Paulo
- RA-10CNEA EzeizaPlanned
- PALLASCurium PettenPlanned
- RMBRMB Radioisotope Processing and Sources Production Unit (N04)Planned
- CNEN, la operación del RMB debe ocurrir integrada con la Unidad de Procesamiento de Radioisótopos y Producción de Fuentes (edificio N04)
- de Oliveira et al. (RMB/CNEN, IPEN), Unlocking New Frontiers: The Versatile Potential of the Brazilian Multipurpose Reactor, arXiv:2510.10657 (Mo-99, Ir-192, I-131, I-125 and Lu-177)
- Curium PettenEurope
- NTP RadioisotopesEurope
- ANSTO Health (Lucas Heights)Africa and Asia-Pacific
- ANSTO, Nuclear medicine (Mo-99 in OPAL, Gentech generators, n.c.a. Lu-177, sodium iodide capsules; 75-80 % of isotopes used in Australia)
- ANSTO, Nuclear medicine facilities (OPAL target plates to the Mo-99 Manufacturing Facility; Gentech generators; Australia and the region)
- ANSTO, Introduction to ANSTO 2023 (OPAL irradiation positions for Mo-99, I-131 and Lu-177; exports to the US East Coast)
- National Academies, Molybdenum-99 for Medical Imaging (2016), ch. 3 Global Production of Molybdenum-99
- MURRNorth America
Supply status by region
Derived from the reactors and processors documented as suppliers of each region. Amber: a current unplanned or extended outage at a reactor or processor serving it. Red: a shortage notice from an authority or the sector's emergency channel in the last fourteen days.
EuropeNo news
No news from the sources in the last 60 days.
North AmericaNo disruption reported
The University of Missouri Research Reactor announced a partnership with Princeton Plasma Physics Laboratory. This collaboration is aimed at supporting the world's largest fusion experiment.
Latin AmericaNo news
No news from the sources in the last 60 days.
Africa and Asia-PacificNo disruption reported
ANSTO recorded a planned shutdown of the OPAL reactor (Lucas Heights) between 30 November and 5 December 2026 in its cycle schedule, classified as planned_shutdown. The dates appear in the schedule preview published on 16 October 2026.
Irradiation reactors
The reactors that irradiate the targets. The status comes from the last availability signal in the last 60 days, and the last signal is the most recent dated document, each with its source.
| Reactor | Power | Status | Last signal |
|---|---|---|---|
HFR Netherlands · NRG PALLAS | 45 MWt | No news | No signals from the sources. |
BR2 Belgium · SCK CEN | 100 MWt | No news | No signals from the sources. |
MARIA Poland · Narodowe Centrum Badań Jądrowych (NCBJ) | 30 MWt | No news | No signals from the sources. |
SAFARI-1 South Africa · Necsa | 20 MWt | No news | No signals from the sources. |
OPAL Australia · ANSTO | 20 MWt | Planned outage | OPAL: planned shutdown from 30 November to 5 December ANSTO · Calendario de ciclos de OPAL y noticias · Oct 23, 2026 · source |
MURR United States · University of Missouri Research Reactor Center | 10 MWt | No news | MURR Univ. Missouri-Columbia announces partnership with physics laboratory MURR · Noticias (University of Missouri Research Reactor) · Oct 21, 2026 · source |
RA-3 Argentina · Comisión Nacional de Energía Atómica (CNEA) | 10 MWt | No news | No signals from the sources. |
IEA-R1 Brazil · IPEN/CNEN | 5 MWt | No news | No signals from the sources. |
| RA-10 Argentina · Comisión Nacional de Energía Atómica (CNEA) | 30 MWt | Under construction | No signals from the sources. |
| PALLAS Netherlands · NRG PALLAS | 55 MWt | Under construction | No signals from the sources. |
| RMB Brazil · Comissão Nacional de Energia Nuclear (CNEN) | 30 MWt | Under construction | No signals from the sources. |
Processors and supply relationships
Documented supply relationships. An amber facility or connection indicates a disruption reported by the supplier.
| Processor | Isotopes | Status | Last signal |
|---|---|---|---|
| RMB Radioisotope Processing and Sources Production Unit (N04) Brazil · Comissão Nacional de Energia Nuclear (CNEN) | Mo-99 / Tc-99m · I-131 · Lu-177 · Ir-192 | Planned | No signals from the sources. |
| Curium Petten Netherlands · Curium | Mo-99 / Tc-99m · Lu-177 · Ir-192 | No news | No signals from the sources. |
| NTP Radioisotopes South Africa · NTP Radioisotopes SOC Ltd (Necsa) | Mo-99 / Tc-99m · I-131 · Lu-177 · Ir-192 | No news | No signals from the sources. |
| ANSTO Health (Lucas Heights) Australia · ANSTO | Mo-99 / Tc-99m · I-131 · Lu-177 | No news | No signals from the sources. |
| CNEA Ezeiza Argentina · Comisión Nacional de Energía Atómica (CNEA) | Mo-99 / Tc-99m · I-131 · Lu-177 | No news | No signals from the sources. |
| IPEN São Paulo Brazil · IPEN/CNEN | Mo-99 / Tc-99m · I-131 · Lu-177 · Ir-192 | No news | No signals from the sources. |
| POLATOM Poland · NCBJ Radioisotope Centre POLATOM | Mo-99 / Tc-99m · I-131 · Lu-177 | No news | No signals from the sources. |
Timeline
Notices from the last 180 days, with dates, issuing organisations and original links.
No events from the sources in this period.
Data: ANSTO · Calendario de ciclos de OPAL y noticias · MURR · Noticias (University of Missouri Research Reactor) · IAEA RRDB · updated on Oct 23, 2026